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A hybrid inorganic–biological artificial photosynthesis system for energy-efficient food production

Elizabeth C. Hann, Sean Overa, Marcus Harland-Dunaway

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Andrés F. Narvaez, Dang N. Le, Martha L. Orozco-Cárdenas, Feng Jiao, Robert E. Jinkerson

2022 · Nature Food

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From the abstract

Abstract Artificial photosynthesis systems are proposed as an efficient alternative route to capture CO 2 to produce additional food for growing global demand. Here a two-step CO 2 electrolyser system was developed to produce a highly concentrated acetate stream with a 57% carbon selectivity (CO 2 to acetate), allowing its direct use for the heterotrophic cultivation of yeast, mushroom-producing fungus and a photosynthetic green alga, in the dark without inputs from biological photosynthesis. An evaluation of nine crop plants found that carbon from exogenously supplied acetate incorporates into biomass through major metabolic pathways. Coupling this approach to existing photovoltaic systems could increase solar-to-food energy conversion efficiency by about fourfold over biological photosynthesis, reducing the solar footprint required. This technology allows for a reimagination of how food can be produced in controlled environments.

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That's a terrible paper. More than half of it is a puff piece on how great it would be if this works. Where's the new work? The process they're writing about seems to be this one: "A hybrid inorganic–biological artificial photosynthesis system for energy-efficient food production" (2022), in "Nature Food"[1] (I had no idea there was a "Nature Food" journal.) The actual conclusion there was that they could force algae growth with this approach, but when they tried lettuce, "... plant growth was largely inhibited by acetate at concentrations that would have measurably increased plant biomass, although some growth parameters such as roots showed increased growth ... Lettuce…
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plants grown with electrolyser-produced effluent ... added to reach a final media concentration of 1.0 mM acetate did not show additional growth inhibition in plant weight or leaf number from secondary electrolysis products Plant tolerance and consumption of acetate as a heterotrophic energy source will need to be increased to fully decouple plants from biological photosynthesis." So, to make this work, it's necessary to bioengineer new food plants that will grow usefully on acetate-enriched water. That's a big project. It's a whole new food chain. Or you can grow algae and make various products of fermentation, and ultraprocess those into something edible. The Impossible Burger's bloody meat "heme" is a product of fermentation of a genetically engineered organism. That's just a flavoring. The product is mostly made from peas and soy. [1] https://www.nature.com/articles/s43016-022-00530-x
namibj
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https://doi.org/10.1038/s43016-022-00530-x feeds nutritional algae, yeast, and a variety of mushrooms ( pearl oyster, blue oyster, elm oyster, coral tooth and enokitake), though the mushrooms were tested with a simulated (I assume this means petrochemically derived, purified, and reconstituted to match the real mixture) analog of the real electrochemical acetate feed, which they tested with the first two organisms. There were also experiments with "undifferentiated lettuce tissue", using C13-labeled acetate to investigate whether crop plants are able to properly feed off of acetate as their main food source, instead of photosynthesis-based small molecules. What I'm…
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suggesting is, roughly, to replace the base starch and maybe (some amount of) base fat in a diet (think a typical Asian diet's rice, or wheat in (historic) European bread+beer[0] diets), so that the overwhelming amount of calories won't need to be supplied in advance. Yeah, that'd likely involve feeding some algae or so with the e.g. synthesized acetate, due to yielding nicer nutrition molecules than e.g. simple glucose, which would be comparatively feasible to synthesize without having to use a bio reactor. Worst case you'd have more sleep in place of productive work for energy conservation reasons, if you need to partially fall back on shipped food due to the food synthesis machines breaking. Recent space fairing history has shown that we can make machines very reliable, especially if they're pretty self-contained, not exposed to/operated in vacuum, and straight-forward to test on earth and in low earth orbit. The ISS crew is just too small to warrant as much of a kitchen facility as needed for incorporating something like "algae-based rice-substitute" or "mushrooms" into their meals, but if Starship works well enough to deploy an unmanned algae production machine for a few months (with solar panels and thermal radiators), before transferring the produce to the ISS to test zero-G food preparation... [0]: that beer was really low %ABV, and more comparable to eating bread with 1:1 watered-down beer to wash it down.

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