The artificial sweetener erythritol and cardiovascular event risk

blood clots: https://www.nature.com/articles/s41591-023-02223-9. Evidence in vitro suggests enhanced platelet activity. Plasma levels of erythritol are sustained for >2d above thresholds associated with platelet hyper-reactivity after consumption of realistic doses. I use artificial sweeteners, but prefer sucralose or anything else to erythritol. I actually don't understand why people still use it (often in 'health food' because it's seen as 'natural'), there are much safer options.

Thanks. This is the study that the article is talking about. The complete paper is https://journals.physiology.org/doi/pdf/10.1152/japplphysiol... It's based on earlier work that suggests that erythritol consumption is associated with increased risk of stroke or myocardial infarction: https://www.nature.com/articles/s41591-023-02223-9

Stevia and many of these other sugar substitutes (like monk fruit sweetener) often come with erythritol (sometimes as the first ingredient!), which has been linked to heart problems. Not sure how valid the article is, but I'll take it as something I just don't need in my diet... https://www.nature.com/articles/s41591-023-02223-9

Naw even that's too charitable. See the linked paper: https://www.nature.com/articles/s41591-023-02223-9 "circulating levels of multiple polyol sweeteners, especially erythritol, were associated with incident (3 year) risk for major adverse cardiovascular events" Wow it's almost like people who are unhealthy know that they are unhealthy and that's why they attempt to reduce their calorie intake. The fact that unhealthy people are 2x as likely to have "adverse cardiovascular events" should not surprise anyone. Articles like this keep trying to find causation where there's only correlation. Trying to control for confounding factors one at a time is a fool's errand: https://gwern.net/everything

The actual paper: https://www.nature.com/articles/s41591-023-02223-9 Sadly sci-hub doesn't have it, it being a new publication. This is quite impactul for me because I used to endulge in some erythritol chocolate, I'll definitely be cutting them out just to be on the safe side.