Skip to content
Back to the collection

Seasonal coronavirus protective immunity is short-lasting

Arthur W. D. Edridge, Joanna Kaczorowska, Alexis C. R. Hoste

Show all 16 authors

Margreet Bakker, Michelle Klein, Katherine Loens, Maarten F. Jebbink, Amy Matser, Cormac M. Kinsella, Paloma Rueda, Margareta Ieven, Herman Goossens, Maria Prins, Patricia Sastre, Martin Deijs, Lia van der Hoek

2020 · Nature Medicine

Read the paper
HN score
0
Mentions
4
Readers
4
Months
4
What’s in a score?

In the conversation

Original HN comments, with labels from simple text rules. A label describes the whole comment and may miss context or irony. Read the discussion to make up your own mind. About the labels

4 selected excerpts · 4 total mentions

raphlinus
Neutral mention · rule
Antibodies wane, but B-cell and T-cell response is important for longer term protection. Fortunately, we have results (including [B] and [T]) that vaccines also induce these memory cell responses. Also, the durability of immunity from coronavirus probably depends on the exact coronavirus. It does seem to be true for SARS, but possibly less so for the seasonal coronaviruses that cause a respectable fraction of common colds[3]. We don't really know yet where SARS-CoV-2 falls on that spectrum. [B]: https://www.medrxiv.org/content/10.1101/2021.07.12.21259864v... [T]: https://www.medrxiv.org/content/10.1101/2021.06.30.21259787v... [3]: https://www.nature.com/articles/s41591-020-1083-1
HarryHirsch
Neutral mention · rule
Meanwhile this study about human coronaviruses tells the exact opposite story: https://www.nature.com/articles/s41591-020-1083-1 A group of Dutch clinicians have been taking blood samples from a cohort of people for 30 years now (it started out as a project to study AIDS/HIV) and measured antibody levels against the other human coronaviruses. They find that people get re-infected after a year or so. There's no reason to believe that the immune system should behave any different towards COVID-19. Given the US government's past track record on the pandemic, right now I'm disinclined to trust the CDC.

Keep following the thread.

More in Other research

More from the same topics.